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Tetrapeptide Supreme Cream

Featuring Retinatural™ Complex, it supports elasticity, visibly firms contours, and smooths texture – revealing well-rested, even, glowing skin.

$98 $980% savings
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Benefits
  • Firm
  • Hydrate
  • Radiance
  • Smooth

This luxurious blend features our signature plant-derived Retinatural™ Complex of bakuchiol and alpine rose paired with a powerful tetrapeptide chosen for both efficacy and safety. Experience improvement in elasticity, visible firmness, and texture while appearance of fine lines diminish. Wake to well-rested, even-toned skin.

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Clinically Demonstrated to:
  • Provides immediate and long-lasting hydration*
  • Improve skin elasticity**
  • Visibly plumps skin **
  • Visibly improves skin firmness***
After four weeks of use:****
  • [ 94% ] reported skin looks and feels firmer
  • [ 91% ] woke up to glowing skin
  • [ 91% ] observed their skin tone looked more even
  • [ 97% ] experienced instant and lasting hydration
  • *Based on 33-subject clinical study after one use and after eight hours
  • **Based on a 33-subject clinical study after four weeks
  • ***Based on a 33-subject clinical study after eight weeks
  • ****Based on a 33-subject consumer perception study after four weeks
    4.7
    Rated 4.7 out of 5 stars
    Based on 171 reviews
    Reviews Summary
    Customers say this cream provides exceptional hydration for dry skin, particularly as a night moisturizer. Many reviews mention its silky, luxurious texture that absorbs well without feeling greasy. Users appreciate its gentle formula for sensitive skin, with frequent comments about waking up to soft, moisturized skin. While most love the product's performance, some note changes from a previous formula, mentioning differences in scent and texture. The cream receives particular praise from those in dry climates, with many describing it as their long-term favorite moisturizer.
    Rating
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    Your skin concerns:
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    171 reviews
    • Maureen K.
      Verified Buyer
      I recommend this product
      Age 65+
      Your skin type: Combination
      Your skin concerns: Fine Lines & Wrinkles
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      12/6/25
      One of my favorites!!

      Helps me keep my skin hydrated during Maine's cold season!

    • Tina O.
      Verified Buyer
      I recommend this product
      Age 65+
      Your skin type: Dry
      Your skin concerns: Dryness, Fine Lines & Wrinkles
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      12/6/25
      Best of all

      Best moisturizer I’ve used in my life! I’ve struggled with dry flakey skin for years. Tetrapetide Supreme cream solved this issue. My skin stays well moisturized, soft and smooth. Thank you!

    • Lindsay
      I recommend this product
      Rated 5 out of 5 stars
      12/6/25
      5 Stars

      This cream is amazing. I have been using it for years. I ran out of it when they were restarting the company and my skin really missed it.

    • Kelli P.
      Verified Buyer
      I recommend this product
      Age 45-54
      Your skin type: Normal
      Your skin concerns: Fine Lines & Wrinkles, Redness
      How long have you used the product? About a month
      Rated 5 out of 5 stars
      12/5/25
      Overnight cream

      I love how moisturized my skin feels the next morning after using this cream overnight.

    • Natali S.
      Verified Buyer
      I recommend this product
      Age 55-64
      Your skin type: Combination
      Your skin concerns: Dryness, Dullness, Fine Lines & Wrinkles
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      12/5/25
      This is supreme cream!

      I use this day and night. Keeps my face from drying out especially in the winter!