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Tetrapeptide Supreme Cream

A rich overnight renewal cream powered by Retinatural® Complex and Tetrapeptide-21 to visibly firm, smooth, and deeply replenish skin.

4.8
Rated 4.8 out of 5 stars
290 Reviews
$98 $98 0% savings
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Benefits
  • Firmness
  • Nourishment
  • Renewal
  • Recovery

Powered by Retinatural® Complex and Tetrapeptide-21, this rich overnight cream helps visibly firm skin, smooth the appearance of fine lines, and deeply replenish moisture to support the skin barrier with lasting hydration. Designed for skin experiencing dryness, loss of elasticity, and visible signs of aging, this deeply comforting formula leaves skin looking smoother, more supple, and restored —transforming your nightly routine into a replenishing renewal ritual.

 

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    4.8
    Rated 4.8 out of 5 stars
    Based on 290 reviews
    Reviews Summary
    Customers say this cream provides exceptional hydration for dry skin, particularly as a night moisturizer. Many reviews mention its silky, luxurious texture that absorbs well without feeling greasy. Users appreciate its gentle formula for sensitive skin, with frequent comments about waking up to soft, moisturized skin. While most love the product's performance, some note changes from a previous formula, mentioning differences in scent and texture. The cream receives particular praise from those in dry climates, with many describing it as their long-term favorite moisturizer.
    Rating
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    290 reviews
    • Mia J.
      Verified Buyer
      I recommend this product
      Age 45-54
      Your skin type: Combination
      Your skin concerns: Fine Lines & Wrinkles, Breakouts
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      7/5/26
      The best I’ve used

      I love this face cream. I’ve used it every night for years now and it has made my face feel and look better than it had for years prior. I’m turning 50 this year but my face looks much younger.

    • Jazzel
      I recommend this product
      Rated 5 out of 5 stars
      7/5/26
      5 Stars

      Amazing product

    • Loretta F.
      Verified Buyer
      I recommend this product
      Age 55-64
      Your skin type: Combination
      Your skin concerns: Dryness, Oily Skin, Dullness
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      7/1/26
      Great night cream!

      I’ve been using the Tetrapeptide Supreme Cream at night for a few years now and I love how it helps to hydrate my skin. It doesn’t feel super heavy going on but it gives my skin a glow. Very happy with this product and would highly recommend it.

    • Melissa A.
      Verified Buyer
      I recommend this product
      Age 55-64
      Your skin type: Dry
      Your skin concerns: Dryness, Fine Lines & Wrinkles
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      6/26/26
      thanks for the supple skin

      this cream is so rich, i love waking up to soft skin.

    • Kristee B.
      Verified Buyer
      I recommend this product
      Age 35-44
      Your skin type: Combination
      Your skin concerns: Fine Lines & Wrinkles
      How long have you used the product? About a week
      Rated 5 out of 5 stars
      6/20/26
      DREAM CREAM

      Incredible pillowy softness- dream cream!