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Tetrapeptide Supreme Cream

A rich overnight renewal cream powered by Retinatural® Complex and Tetrapeptide-21 to visibly firm, smooth, and deeply replenish skin.

4.8
Rated 4.8 out of 5 stars
277 Reviews
$98 $98 0% savings
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Benefits
  • Firmness
  • Nourishment
  • Renewal
  • Recovery

Powered by Retinatural® Complex and Tetrapeptide-21, this rich overnight cream helps visibly firm skin, smooth the appearance of fine lines, and deeply replenish moisture to support the skin barrier with lasting hydration. Designed for skin experiencing dryness, loss of elasticity, and visible signs of aging, this deeply comforting formula leaves skin looking smoother, more supple, and restored —transforming your nightly routine into a replenishing renewal ritual.

 

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    4.8
    Rated 4.8 out of 5 stars
    Based on 277 reviews
    Reviews Summary
    Customers say this cream provides exceptional hydration for dry skin, particularly as a night moisturizer. Many reviews mention its silky, luxurious texture that absorbs well without feeling greasy. Users appreciate its gentle formula for sensitive skin, with frequent comments about waking up to soft, moisturized skin. While most love the product's performance, some note changes from a previous formula, mentioning differences in scent and texture. The cream receives particular praise from those in dry climates, with many describing it as their long-term favorite moisturizer.
    Rating
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    277 reviews
    • Pam P.
      Verified Buyer
      I recommend this product
      Age 65+
      Your skin type: Combination
      Your skin concerns: Fine Lines & Wrinkles, Dryness
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      6/5/26
      Skin Smoother

      I personally like to use the tetrapeptide supreme cream before using foundation. My skin looks smoother and the foundation brushes on more evenly.

    • Rachel C.
      Verified Buyer
      I recommend this product
      Age 35-44
      Your skin type: Combination
      Your skin concerns: Oily Skin, Dryness, Fine Lines & Wrinkles
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      6/4/26
      Best night cream

      This is my favorite night time moisturizer, and I use it year round (smaller dab in the warmer months).

    • Amber H.
      Verified Buyer
      I recommend this product
      Age 45-54
      Your skin type: Dry
      Your skin concerns: Fine Lines & Wrinkles
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      6/3/26
      Love this cream!

      It’s so moisturizing! My aging skin loves it!

    • Blair K.
      Verified Buyer
      I recommend this product
      Age 35-44
      Your skin type: Dry, Oily, Combination
      Your skin concerns: Breakouts, Dryness, Oily Skin, Fine Lines & Wrinkles
      How long have you used the product? About a month
      Rated 5 out of 5 stars
      6/2/26
      Perfectly hydrating

      A little goes a long way. It does not leave my face feeling greasy. I use before bed and sometimes in the morning. Have noticed less dry spots on my face.

    • Linda M.
      Verified Buyer
      I recommend this product
      Age 65+
      Your skin type: Normal
      Your skin concerns: Fine Lines & Wrinkles
      How long have you used the product? Over a month
      Rated 5 out of 5 stars
      6/2/26
      Favorite!

      I love this eye cream! It makes the skin feel so smooth! I’m lost without it!